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Necrosis and Apoptosis Pathways

English 10 leveled MCQs Free

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1

Pathway of Necrosis and Apoptosis with diagram or flow chart

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7 marks Long answer

Discuss the consequences of dysregulated apoptosis in diseases.

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Dysregulated apoptosis can lead to cancer, neurodegenerative diseases, and autoimmune disorders due to excessive or insufficient cell death.

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6 marks Long answer

Explain how cellular signaling influences apoptosis.

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Cellular signaling pathways regulate apoptosis by activating or inhibiting pro-apoptotic and anti-apoptotic proteins.

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5 marks Long answer

Draw a flow chart illustrating the pathways of necrosis and apoptosis.

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Flow chart should depict necrosis and apoptosis pathways, including key steps and molecules involved.

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4 marks Medium answer

Explain the mitochondrial pathway of apoptosis.

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The mitochondrial pathway involves the release of cytochrome c from mitochondria, activating caspases.

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4 marks Medium answer

Differentiate between the intrinsic and extrinsic pathways of apoptosis.

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The intrinsic pathway is triggered by internal signals (e.g., DNA damage), while the extrinsic pathway is activated by external signals (e.g., death ligands).

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3 marks Medium answer

What role do caspases play in apoptosis?

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Caspases are proteases that execute apoptosis by cleaving specific cellular substrates.

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3 marks Medium answer

Describe the inflammatory response associated with necrosis.

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Necrosis triggers an inflammatory response characterized by immune cell recruitment and release of pro-inflammatory cytokines.

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2 marks Short answer

List two key differences between necrosis and apoptosis.

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Necrosis is uncontrolled and causes inflammation; apoptosis is controlled and does not cause inflammation.

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1 marks Short answer

Define necrosis.

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Necrosis is uncontrolled cell death due to injury or disease.

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1 marks Short answer

Define apoptosis.

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Apoptosis is programmed cell death that occurs in a regulated manner.

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