Antifungal Drugs: Pharmacology for D.Pharm 2nd Year

Antifungal drugs are agents used to treat fungal infections by targeting structures or processes unique to fungal cells, such as ergosterol synthesis or cell wall components. This topic covers the major classes — polyene…

• Fungi are eukaryotes, so antifungals have narrower selective toxicity than antibacterials.
• The fungal cell wall (chitin, β-glucan) is absent in human cells and is targeted by echinocandins.
• Ergosterol is the fungal membrane sterol; cholesterol is the human equivalent.

Full explanation, worked examples & memory tricks in the app