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Pharmaceutical Analysis Exam Prep

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Pharmaceutical Analysis Exam Prep

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Sample questions with model answers

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10 marks Long answer

Define errors and analyse the concept of various determinate errors. Suggest the different methods to minimize determinate errors

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Errors are deviations from true values; minimize by calibration and proper technique.

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10 marks Long answer

A. Define primary standards with illustrative examples and mention the qualities of a primary standard.

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Primary standards are pure substances used in titrations; qualities include stability and high purity.

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10 marks Long answer

B. Define molarity, molality, mole fraction, normality, and mass percent.

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Molarity is moles of solute per liter of solution; molality is moles per kg of solvent, etc.

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4 marks Medium answer

Apply the concept of conductance in the titration of HCl vs NaOH and CH$_3$COOH vs NaOH. Draw and explain the titration curves for both cases.

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Conductance changes during titration; curves show distinct endpoints for strong vs weak acids.

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4 marks Medium answer

How do you prepare 0.1 N solution of Sulfuric acid and standardize it?

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Dilute concentrated H$_2$SO$_4$ to 0.1 N and standardize using NaOH.

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4 marks Medium answer

Explain the method of preparation of 0.1 N NaOH and its standardization.

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Dissolve NaOH in water to prepare 0.1 N and standardize against KHP.

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1 marks Short answer

Amount of Na$_2$CO$_3$ to be dissolved to get decinormal solution in 250 mL of water is

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2.52 g

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1 marks Short answer

18 g of glucose is dissolved in 18 g of water; then the mole fraction of glucose is

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0.09

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1 marks Short answer

0.052 has how many significant figures?

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2

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1 marks Short answer

Na$_2$S$_2$O$_3$ is standardized by using

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KMnO$_4$

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1 marks Short answer

The molarity of 5N H$_2$SO$_4$ is

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2.5 M

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1 marks Short answer

Which of the following is an alkaline primary standard?

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Na$_2$CO$_3$

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1 marks Short answer

Which of the following indicators is used in acidic pH range in acid-base titrations?

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Methyl orange

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1 marks Short answer

NaOH cannot be used as primary standard because

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It is hygroscopic

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1 marks Short answer

Unit of specific conductance is

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Ohm$^{-1}$ cm$^{-1}$

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1 marks Short answer

Indicator used in standardization of ceric ammonium sulphate by using ferric ammonium sulphate is

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Ferroin

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1 marks Short answer

Compounds that induce vomiting are called __________.

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emetics

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1 marks Short answer

The composition of BaSO$_4$ reagent includes:

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BaCl$_2$, K$_2$SO$_4$ & Alcohol

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1 marks Short answer

Among the following which is not a toxic heavy metal?

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Iron

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1 marks Short answer

Increased secretion of hydrochloric acid in stomach leads to:

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Hyperchlorhydria

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1 marks Short answer

Which compound is known as blue vitriol?

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CuSO$_4$

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1 marks Short answer

Assay of sodium thiosulphate is done by __________ type of titration.

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Iodometry

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1 marks Short answer

Which of the following is used in treating anaemia?

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FeSO$_4$

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1 marks Short answer

Purified water is prepared by __________ method.

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All the above

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1 marks Short answer

In the Limit test for Lead, the original colour of dithizone in chloroform is

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Violet

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1 marks Short answer

The concentration of standard solution of sulphate in sulphate limit test is

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0.1089% w/v solution of K$_2$SO$_4$

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1 marks Short answer

The composition BaSO$_4$ reagent includes

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BaCl$_2$, K$_2$SO$_4$ & Alcohol

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