Cell Membrane: 17 flashcards

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1. What is the primary structural framework of the cell membrane?

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A phospholipid bilayer, with hydrophilic heads facing outward and hydrophobic tails facing inward.

2. Name the model that describes the cell membrane as a fluid mosaic.

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The Fluid Mosaic Model, proposed by Singer and Nicolson in 1972.

3. What does 'fluid' refer to in the Fluid Mosaic Model?

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The ability of lipids and proteins to move laterally within the membrane, giving it flexibility and dynamic behavior.

4. What does 'mosaic' refer to in the Fluid Mosaic Model?

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The patchwork of different components (phospholipids, proteins, cholesterol, carbohydrates) embedded in the membrane.

5. List the four main components of the cell membrane.

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Phospholipids, proteins (integral and peripheral), cholesterol, and carbohydrates (glycolipids and glycoproteins).

6. What is the role of cholesterol in the cell membrane?

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It stabilizes membrane fluidity, reducing fluidity at high temperatures and preventing solidification at low temperatures.

7. What are integral (transmembrane) proteins?

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Proteins that span the entire lipid bilayer, often serving as channels, transporters, or receptors.

8. What are peripheral proteins?

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Proteins that are loosely attached to the surface of the membrane (either inner or outer), often involved in signaling or structural support.

9. What is the primary function of membrane carbohydrates?

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They are involved in cell-cell recognition, adhesion, and as receptors (forming glycoproteins and glycolipids).

10. What is selective permeability?

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The property of the cell membrane that allows some substances to pass through while blocking others, maintaining internal balance.

11. Which types of molecules can easily pass through the lipid bilayer by simple diffusion?

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Small, nonpolar (hydrophobic) molecules like oxygen, carbon dioxide, and nitrogen, as well as small uncharged polar molecules like water (to a limited extent).

12. What is facilitated diffusion?

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The passive movement of molecules (like glucose or ions) across the membrane through specific transport proteins (channels or carriers), without energy input.

13. What is active transport?

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The movement of molecules against their concentration gradient, requiring energy (ATP) and specific transport proteins (pumps).

14. Give an example of active transport in cells.

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The sodium-potassium pump, which moves Na+ out and K+ into the cell against their gradients.

15. What is endocytosis?

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The process by which the cell membrane engulfs large particles or fluids to bring them into the cell, forming a vesicle.

16. What is exocytosis?

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The process by which vesicles fuse with the cell membrane to release their contents outside the cell.

17. Why is the cell membrane described as 'asymmetric'?

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Because the outer and inner faces have different lipid and protein compositions, which is crucial for their distinct functions (e.g., extracellular carbohydrates vs. intracellular cytoskeletal attachments).

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